In human ovarian cancer, the expression levels of glucose metabolism-related genes and proteins, such as Glut1, Glut3, HIF-1α, and glucose-6-phosphate isomerase, were significantly upregulated compared with those in benign ovarian tumors and healthy controls, as well as CD4+ Teffs [141], in agreement with the data from a study based on colorectal cancer and liver cancer [140, 142]. The gene discussed is HIF1A; the disease is ovarian cancer.