Given the role of the anterior cingulate cortex (ACC) in integrating cognition with emotion [36–38], its link with mental disorders [39], and the high level of RBFOX1 expression in this brain area (Supplementary Fig. 3), we assessed the effects of rs6500744 on dorsal ACC (dACC) activation during implicit emotion processing and executive functioning. Here, RBFOX1 is linked to mental disorder.