We found that CSF GFAP and YKL-40 levels were closely associated with several neuroinflammatory proteins previously associated with AD progression, such as CX3CL1 [63], MMP-10 [64], TRAIL [65], HGF [66], CSF-1 [67], and 4E-BP1 [68]. This evidence concerns the gene CX3CL1 and Alzheimer disease.