Tumours with SB insertions in the 5′ region of Fgfr2 either contained a second SB insertion in I17 or contained rearrangements (REs) in Fgfr2-I17, producing gene fusions11 and therefore also expressing Fgfr2ΔE18 (Extended Data Fig. 1d). This evidence concerns the gene FGFR2 and neoplasm.