Tumor-bearing status (HR = 1.819, 95%CI = 1.137–2.911, P = 0.013) and MMP1 expression (HR = 1.236, 95%CI = 1.037–1.473, P = 0.018) were independent factors impacting the OS of patients with LIHC (Table 4). The gene discussed is MMP1; the disease is neoplasm.