To define the putative role of Bmal1 in tumor progression of the intestinal epithelium, we profiled gene expression using RNA sequencing (RNA-seq) from three independent biological replicates of late-passage WT, Bmal1−/−, Apc+/−, and Apc+/−;Bmal1−/− organoids. This evidence concerns the gene BMAL1 and neoplasm.