The results of gene expression levels for pro-apoptotic Bax, caspase 9, caspase 3, and anti-apoptotic Bcl-2 genes in HCC-induced mice revealed that Bax, caspase 9, and caspase 3 were significantly downregulated, while Bcl-2 was significantly upregulated, compared to normal groups. The gene discussed is CASP9; the disease is hepatocellular carcinoma.