Hox transcript antisense intergenic RNA (HOTAIR) is transcribed from the antisense sequence of the HOXC gene, which consists of 6 exons located on chromosome 12q13.13.9 Expression of HOTAIR has been reported to be irregular in breast, stomach, pancreatic, hepatocellular, lung, and CRCs.10,11 Therefore, it is considered effective in cancer development, progression, and metastasis. Here, HOTAIR is linked to cancer.