C-reactive protein has been shown to increase significantly after appendix perforation or abscess development.26 White blood cell and CRP levels were not detected as a predictive factor for perforation in AA in another study conducted by Güler et al.27 In our study, we determined the cut-off value of CRP to be 7.30 mg/L to predict the diagnosis of AA in moderate-risk patients according to ASS, and appendicitis was shown in CT imaging. This evidence concerns the gene CRP and appendicitis.