Loss of miR-24-3p promotes epithelial cell apoptosis and impairs the recovery from intestinal inflammation.38 MiR-200b-3p alleviates TNF-α-induced apoptosis and inflammation of intestinal epithelial cells and ulcerative colitis progression in rats.39 Here, we identified that miR-222-3p has a binding site for SOCS1 by bioinformatics analysis and confirmed their targeted relationship. The gene discussed is TNF; the disease is inflammatory response.