Results for the entire 0- to 72-h infection time course show that FoxO3a localized to the nucleus from 6 hpi through the end of the experiment in cells expressing kinase-dead myr-Akt, while myr-Akt-expressing cells failed to show FoxO3a nuclear localization at any time point, despite the fact that the viral antigen IE1 was detected in nuclei of both myr-Akt and K179M settings from 6 hpi on. Here, FOXO3 is linked to infection.