PTGS2 and colorectal cancer: In addition, C-PC is a selective inhibitor of cyclooxygenase-2 (COX-2) and promotes apoptosis in lipopolysaccharide-stimulated Raw 264.7 macrophages (the Raw 264.7 cells are monocyte/macrophages-like cells [71]) [34], which have shown a tremendous pharmacological effect in treating colorectal cancer [23].