METTL3 and Familial prostate cancer: Studies showed that METTL3 regulates LEF1 [199], KIF3C [200], USP4 [201], GLI1 [202], ITGB1 [170], IGF1R [203], and lncRNA PCAT6 [203] expression in an m6A-dependent manner to promote prostate cancer malignant progression.