Studies have found that WTAP affects the MAPK [52], AKT [52], Wnt [53, 54], and NF-κB [55] signaling pathways and promotes tumor progression by regulating the downstream targets EGR3 [56], HK2 [57], ETS1 [58], and CAV-1 [55]. Here, NFKB1 is linked to neoplasm.