In addition to the JAK2 V617F variant pairs, immune thrombocytopenia, essential thrombocythemia, and chronic myeloproliferative disease were connected by SELENON G315S, which is indicated as pathogenic by ClinVar and has been associated with congenital myopathies among other diseases [51, 52]. This evidence concerns the gene JAK2 and autoimmune thrombocytopenic purpura.