KD is a rare, chronic inflammatory disease of unknown etiology, and its prominent clinical features include subcutaneous masses on the head and neck, accompanied by elevated serum IgE levels, peripheral blood eosinophilia, and histopathological characteristics, including preserved nodal architecture, florid germinal center hyperplasia, eosinophilic infiltration, postcapillary venule proliferation, and eosinophilic abscesses [2]. The gene discussed is IGHE; the disease is Increased total eosinophil count.