Furthermore, high score tumors enriched hypoxia, xenobiotic metabolism, epithelial–mesenchymal transition (EMT), UV response up, apical junction, Mtorc1 response, and angiogenesis in the ER-positive/HER2-negative breast cancer cohort, but not in the TNBC cohort (Fig. 5b). This evidence concerns the gene ERBB2 and breast carcinoma.