SDF-1α is a substrate of DPP4 enzyme and DPP4 inhibition preserves SDF-1α actions and promotes cardiac recovery after I/R (Pala and Rotella 2013), acute myocardial infarction (Li et al. 2019), or stroke (Chiazza et al. 2018). This evidence concerns the gene CXCL12 and myocardial infarction.