Consistently, the correlation of the IPRP score was negatively correlated with the content of CD8 + T cells and positively correlated with the CD4 + T cells in KIRC, and the content of CD8 + T cell in the high risk group was greater than that in the low risk group (Supplementary Fig. 18), which is opposite to AML (Supplementary Fig. 15). This evidence concerns the gene CD4 and acute myeloid leukemia.