Other BMs revealed to be associated with obesity-related HF are suggestive of mechanisms associated with apoptosis (TNFRSF10A) [21], inflammation (ST6GAL1 and GAL-9) [22] and fibrosis (MMP12, TIMP1 and QPCT) [23, 24]. This evidence concerns the gene LGALS9 and obesity due to melanocortin 4 receptor deficiency.