GFPT1 and neoplasm: Consequently, GFAT1 deletion-suppressed cell growth was found notably rescued by WT rGFAT1 but not by rGFAT1-H577A expression under glucose deprivation (Fig. 1g; Supplementary Fig. S1i); similar effect was also verified in tumor growth analysis in nude mice (Fig. 1h), revealing the importance of metabolic activity of GFAT1 in cell growth.