We found that cell migration/invasion abilities were significantly reduced in the primary ccRCC cells upon DPF3 knockdown (Fig. 2a), whereas only DPF3a-OE in 786-O cells could increase migration/invasion capabilities at 12 to 24 h, respectively, after seeding (Fig. 2b). The gene discussed is DPF3; the disease is nonpapillary renal cell carcinoma.