Of these, ABHD12, VPS11, ATX10, AFG3L2, and ROGDI are all associated with neurological disorders (respectively, PHARC syndrome (53), hypomyelinating leukodystrophy 12 (54), spinocerebellar ataxia type 10 (59) and 28 (56, 60), and Kohlschutter’s syndrome (58)) (supplemental Table S6). Here, VPS11 is linked to Amelo-cerebro-hypohidrotic syndrome.