Aberrant expression of PD-L1 has been shown to have an association with the undesirable prognosis of several kinds of cancers.20, 21Several studies have reported the upregulated expression of PD-L1 in lymphoma and illustrated its association with the prognosis of DLBCL23, 24however, the prognostic role of PD-L1 expression in DLBCL remains unclear. The gene discussed is CD274; the disease is cancer.