AR and neoplasm: For the 125 samples with expression data available, we observed that AR gene expression was higher in the coamplification and selective enhancer categories compared with samples with no amplification, after accounting for tumor purity and ploidy (ANCOVA/Tukey’s honestly significant difference [HSD] P values 5.6 × 10–11 and 4.5 × 10–4, respectively), but not for selective AR status (ANCOVA, P = 0.098) (Figure 3B).