IPA of MYOC/CCL19 fibroblast gene expression correlating with the mRSS revealed several prominent pathways: senescence, hepatic fibrosis signaling, IL-6 signaling, STAT3 signaling, TGF-β signaling, protein ubiquitination, JAK/Stat signaling, and role of JAK1, JAK2 and TYK2 in interferon signaling. This evidence concerns the gene TYK2 and Hepatic fibrosis.