Allogeneic hematopoietic stem cell transplant (HSCT) has become the acknowledged standard for FMS-like tyrosine kinase internal tandem duplication (FLT3–ITD) harboring acute myeloid leukemia (AML) [1] based on two large studies, showing a long-term overall survival (OS) of > 50% for patients receiving HSCT in first complete remission (CR) [2, 3]. Here, FLT3 is linked to acute myeloid leukemia.