FLT3 and acute myeloid leukemia: Since the RATIFY trial [4] reported a statistically significant overall survival benefit for midostaurin combinations in induction/consolidation chemotherapy and the ADMIRAL trial [5] showed a significant survival advantage for gilteritinib alone over salvage chemotherapy in relapsed/refractory FLT3-mutated AML patients, routine incorporation of FLT3 inhibitors in these patients is evolving.