In contrast, meningiomas harboring an AKT1 mutation were predominantly located in the cervical spine (73.3%) and 87% of AKT1-mutant meningiomas (n = 13) (compared to 43.75% of NF2-mutant meningiomas, n = 14) arose ventrally or ventro-laterally to the spinal cord (p = 0.010). The gene discussed is AKT1; the disease is meningioma.