Arcangeli and colleagues were the first to reveal the existence of pathophysiological links between integrins and K+ channels, when they showed that murine erythroleukemia cell adhesion to fibronectin, and neurite outgrowth of neuroblastoma cells were associated with a potassium current, later attributed to the voltage-gated K+ channel KCNH2 (synonyms, Kv11.1, HERG, and hERG1) [67,74–78]. Here, KCNH2 is linked to neuroblastoma.