KCNB1 and early-onset autosomal dominant Alzheimer disease: Dasatinib was also found to significantly decrease inflammation and neurodegeneration caused by oxidation of integrin-α5-KCNB1 complexes in the Lateral Fluid Percussion (LFP) mouse model of brain trauma, a condition that shares with Alzheimer’s disease copious oxidative stress and Aβ plaque formation [115–120].