In addition, we identified that miR-147a directly bound to the 3′-UTR of SLC40A1, induced intracellular iron accumulation, and ultimately resulted in lipid peroxidation and ferroptosis, and that SLC40A1 overexpression significantly blocked the miR-147a mimic-mediated tumor suppression in human glioblastoma cells in vitro. The gene discussed is SLC40A1; the disease is glioblastoma.