ADAR1 expression was promoted in Caco2 CRC cells treated with 5FU (p < 0.05), CPT-11 (p < 0.001), or OX (p < 0.001) and at a dose of 8 Gy, or with 5FU (p < 0.01), CPT-11 (p < 0.05), or OX (p < 0.001) and at a dose of 16 Gy (Fig. 4E). The gene discussed is HCRT; the disease is colorectal carcinoma.