ADAR and colorectal carcinoma: ADAR1 expression was promoted to a larger extent in CRC lesions treated with chemoradiation therapy, which included OX (CAPOX-RT), in comparison with ADAR1 expression in CRC lesions treated with a FOFOXIRI (5FU + OX + CPT-11) chemo-regimen (p < 0.001; Fig. 6B).