VWA5A and breast cancer: These clusters, which we named BC Sub-Clusters 1–4 (BCSC1-4; Fig. 2a, Supplementary Fig. 3a), confirmed our previous observations of the BC architecture that were anchored on MORN1 (BCSC-1), IMC9/13 (BCSC-2), IMC5/8 (BCSC-3) and Cen2 (BCSC-4)7.