Ten potential pathogenic mutations (in the SERPINB2-, CNTNAP4-, DENND4B-, DPP4-, FGFBP2-, MIGA2-, POLE-, SNRNP40-, TOP2B- and ZDHHC18 genes) could be identified and confirmed in individual cases, yet no mutation was observed in more than one of the 50 analysed cases (including also chronic pancreatitis). This evidence concerns the gene DENND4B and chronic pancreatitis.