Patients with increasing SARS-CoV-2severity often have leukocytosis, leukopenia, decreased albumin levels,increased levels of lactate dehydrogenase (LDH), CRP, bilirubin, andcreatinine kinase, and a high erythrocyte sedimentation rate (ESR).324 In general, no individual biomarker can beused to confirm or discard COVID-19 diagnosis, and diagnostic testingshould be conducted for all suspected cases. This evidence concerns the gene CRP and Increased total leukocyte count.