Among the classified cell types—classical (CD14++CD16–), intermediate (CD14++CD16+) and non-classical (CD14+CD16++) monocytes, conventional dendritic cells and plasmacytoid dendritic cells (pDCs)—DOCK2 expression was highest in the non-classical monocytes, which have been implicated in the pathophysiology of COVID-19 (refs. 26,27) (Fig. 2h–j). Here, DOCK2 is linked to COVID-19.