The mRNA expression of CCL3, CCL4, and CSF1 was significantly upregulated in IL17D–expressing A549 cells compared with that in control cells (Figure 4A), whereas IL17D overexpression in the murine lung cancer cell line LLC1 increased Ccl3, Ccl4, and Il6 expression (Figure 4B). The gene discussed is CCL4; the disease is lung carcinoma.