We identified 9 HLA alleles across 3 genes (6 for DQB1 [OMIM 604305], 2 for DPB1 [OMIM 142858], and one for DRB1 [OMIM 142857]) that had P values exceeding genome-wide significance (ie, <5 × 10−8); Seven alleles were positively associated with HL risk, and 2 alleles were negatively associated with it (Table 2). The gene discussed is HLA-DPB1; the disease is Hodgkins lymphoma.