PVT1 and leukemia: AHI1 is a prerequisite for development of the cerebellum and cortex in humans, and perturbations in AHI1 expression may result in specific subtypes of human leukemia.34 Third, we identified rs13279159 (OR, 1.33; 95% CI, 1.20-1.47; P = 1.7 × 10−8) at 8q24.21, with a high LD (r2 = 0.75, D′ = 1.00) with previously reported rs2019960,19 located at a 82-Kb LD block telomeric to PVT1 (OMIM 165140), which represents a long noncoding RNA associated with acute myeloid leukemia and HL.