ABCG2 and gout: Previously, several studies have shown the association of gout with ABCG2 polymorphisms [15–17], the stronger effects of common dysfunctional ABCG2 variants in the risk of hyperuricemia/gout than major environmental risk factors such as age, obesity, and heavy drinking [18], as well as in the earlier onset of gout and the presence of a familial gout history [19, 20].