Molecular studies were performed using the next-generation sequencing of surfactant dysfunction genes identified three mutations in surfactant protein-C gene (SFTPC) in 6 Chinese children with ILD symptoms, whose ages of onset ranged from 7 days to 15 months: I73Tin 4/6, D105G in 1/6, and Y113H in 1/6 patients [37]. The gene discussed is SFTPC; the disease is interstitial lung disease.