In the present study, sequencing analysis of SFTPC gene within 20 ILD patients revealed five variants: c.42+35G>A (rs8192340), c.43-21T>C (rs13248346), c.436-26C>G (rs2070687), c.413C>A (rs4715), and c.557G>A (rs1124). This evidence concerns the gene SFTPC and interstitial lung disease.