HTT and Huntington disease: This point is debated as the MW1 selectivity for mHTT can be influenced by a number of factor such as poly-glutamine repeat length and HTT proteoforms, but here we used MW1 for the immuno-depletion of mHTT in human HD CSF as a means for the preliminary validation of the specificity of the CHDI_HTT_143 (2B7-D7F7) polyglutamine length-independent assay, whereas studies for the assessment of the MW1 selectivity are outside the scope of the present work.