Because of the width of this topic, in this section we mainly discuss the implications of mTOR signaling pathway in keratinocyte carcinomas (also known as non-melanoma skin cancers, NMSC), in particular basal cell carcinoma (BCC) and squamous cell carcinoma (SCC), and inflammatory skin diseases, such as psoriasis and AD. Here, MTOR is linked to skin basal cell carcinoma.