COL1A2 and gastric cancer: In a bioinformatics analysis conducted by Xu et al. (2021), the expressions of ITGB1 and alpha-2 collagen type I (COL1A2) were significantly increased in GC tissues, and 63 characteristic DEGs were mainly involved in regulating extracellular matrix (ECM)–receptor interactions and the PI3K-Akt signaling pathway.