Adding miR-138-5p inhibitor or overexpression of SIRT7 partially reversed the DNA damage phenotype caused by circ-ZNF609 depletion, and circ-ZNF609 depletion reduced the tumor size, tumor volume, and tumor weight through the miR-138-5p/SIRT7 axis in vivo (Liu et al., 2021b). This evidence concerns the gene ZNF609 and neoplasm.