RUNX1T1 and acute myeloid leukemia: t (8;21) AML related to the RUNX1-RUNX1T1 (AML1-ETO, AE) fusion gene, accounts for approximately 7% of adult primary AML (Arber et al., 2016; Faber et al., 2016; Papaemmanuil et al., 2016; Döhner et al., 2017).