CDH6 positively correlated with CCR5, C‐C motif chemokine ligand (CCL) 5, IL12 receptor subunit beta 1, IL2 receptor gamma, IFN gamma receptor 2, and many other cytokines, indicating an important role of CDH6 in signal transmission and different immune processes in the glioma microenvironment. The gene discussed is CCR5; the disease is glioma.