CDH6 positively correlated with CCR5, C‐C motif chemokine ligand (CCL) 5, IL12 receptor subunit beta 1, IL2 receptor gamma, IFN gamma receptor 2, and many other cytokines, indicating an important role of CDH6 in signal transmission and different immune processes in the glioma microenvironment. This evidence concerns the gene IFNGR2 and glioma.