Moreover, highly expressed NLRP1 was positively correlated with the infiltration level of plasma cells, CD4 + T cells, CD8 + T cells, macrophages, dendritic cells (DCs), NK cells, monocytes, neutrophils, regulatory T cells (Tregs), mast cells, endothelial cells, and cancer-associated fibroblast cells, while was negatively associated with tumor purity (Supplementary Figure S11D). This evidence concerns the gene CD8A and cancer.