To determine whether the different infection efficiencies of SARS‐CoV‐2 under different pH conditions are caused by pH‐dependent ACE2 expression regulation in cells, we treated HEK293T‐ACE2 cells (Figure 4A,B) or HUVECs (Figure 4C,D) and found no apparent difference in total ACE2 protein expression under the different pH conditions. The gene discussed is ACE2; the disease is infection.