Anti-insulin (IAA), anti-glutamic acid decarboxylase (anti-GAD), anti-islet antigen 2 (anti-IA2), and anti-zinc transporter-8 (ZnT8) autoantibodies are detected in up to 100% of children developing diabetes before 5 years of age and with a lower prevalence in individuals who may only carry some of these autoantibodies (13). Here, INS is linked to diabetes mellitus.