For fitting to scRNA-based monocyte phenotypes, we selected circulating monocyte mRNA series from postmenopausal osteoporotic patients (GSE56815) and from carotid atherosclerosis patients (GSE23746), both of which were isolated by negative selection with CD3, CD7, CD16, CD19, CD56, CD123 and CD235a (Miltenyi - Monocyte Isolation Kit II) (21, 22). This evidence concerns the gene IL3RA and carotid atherosclerosis.