The clinical decision curve for sepsis in infected patients demonstrated that when the threshold probability of IL-10 detection alone was 8%-100%, the threshold probability of IL-17 detection alone was 6%-93 %, the threshold probability of PCT detection alone was 6%-100 %, and the probability of the three combined detection thresholds was 1%-100 %, the predictive model's net clinical benefit was significant. The gene discussed is IL10; the disease is Sepsis.