CXCL13 and viral encephalitis: Factors mentioned in this part are mainly Th17 cell-associated. Th17 cells accumulation is correlated with poor prognosis of AE, especially anti-NMDAR AE. CXCK13 may be a potential marker of treatment response and relapse rate. Meanwhile, as indicators for B cell and T cell respectively, CXCL13 and CXCL10 can reflect the disease process as B cells take part in abnormal inflammatory activation in the early stages of the disease whereas T cells participate in immune regulation Neopterin can reflect the acute and recurrent encephalitis during diagnosis.