S100 protein: ↑ in anti-NMDAR and anti-DPPX encephalitis PGRN: ↑ in anti-NMDAR encephalitis Nfl:↑ in anti-NMDAR and anti-LGI1 encephalitis GFAP: ↑ in anti-NMDAR and limbic encephalitis Total-tau: ↑ in anti-NMDAR encephalitis. The gene discussed is LGI1; the disease is encephalitis.